- Dance Companies, North Port
- Darts & Dart Boards Supplies, North Port
- Day Spas, North Port
- Deciduous Tree Fruits, North Port
- Deck Cleaning & Restoration, North Port - Clean & Seal Decks, Patios, Fences, etc
- Deck, Patio & Gazebo Design, Building, Cleaning, Repair & Maintenance Contractors, North Port
- Decorating & Designing Services, North Port
- Decorative & Stamped Concrete, North Port
- Delicatessen Restaurants, North Port
- Delivery & Errand Services, North Port
- Denomination, Non-Denominational, Etcetera, North Port
- Dental Bonding & Cosmetic Dentistry, North Port - Cosmetic Dentist & Tooth Bonding
- Dentists, North Port
- Department Stores, North Port
- Dialysis Clinics, North Port - Kidney Dialysis Centers
- Diner Restaurants, North Port
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- Direct Mail Advertising Services, North Port
- Disc Jockeys, North Port
- Discount Stores, North Port - Clothing, Grocery, Furniture, Etc
- Doctors, Physicians & Surgeons, North Port
- Donuts, North Port
- Doors & Door Frames, North Port - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Dressmaking & Sewing Schools, North Port
- Drinking Establishments, North Port
- Drug Screening Services, North Port
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, North Port
- Dry Cleaning & Laundry, North Port - Dry Cleaners
- Dryer Vent Cleaning, Repair & Installation, North Port
- Dryers Sales, Service & Repair, North Port - Gas & Electric
- Drywall, Insulation & Plaster Contractors, North Port - Installation & Repair Services
- Durable & Non Durable Goods & Products, North Port
- Durable Goods & Products, North Port
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