- Dance Companies, Sanibel
- Day Spas, Sanibel
- Decorating & Designing Services, Sanibel
- Decorative Wood Products Manufacturers, Sanibel
- Delicatessen Restaurants, Sanibel
- Dental Bonding & Cosmetic Dentistry, Sanibel - Cosmetic Dentist & Tooth Bonding
- Dentists, Sanibel
- Department Stores, Sanibel
- Diamonds & Precious & Semi-Precious Stones, Sanibel
- Direct Mail Advertising Services, Sanibel
- Doctorate Degree, Sanibel
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- Doctors, Physicians & Surgeons, Sanibel
- Donuts, Sanibel
- Door Glass & Mirrors, Sanibel
- Doors & Door Frames, Sanibel - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drinking Establishments, Sanibel
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Sanibel
- Dry Cleaning & Laundry, Sanibel - Dry Cleaners
- Dryers Sales, Service & Repair, Sanibel - Gas & Electric
- Dumpster Rental, Sanibel
- Dwelling Operators Except Apartment, Sanibel
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