- Office Partitions & Dividers, Port Richey
- Office Supplies, Equipment & Office Furniture Stores, Port Richey
- Oil & Gas Exploration & Development, Port Richey - Oil Field Exploration, Monitoring & Remediation
- Oil Change & Lubrication, Port Richey - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Port Richey - Oil Companies
- Ophthalmologists, Port Richey - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Goods Repair & Service, Port Richey - Camera Repair
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Port Richey
- Opticians, Port Richey
- Optometrists, Port Richey - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Nursery, Port Richey
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- Ornamental Nursery Services, Port Richey
- Orthopedic & Prosthetic Appliances & Shoes, Port Richey - Orthopedic Shoes
- Orthopedists, Port Richey - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Building Materials & Supplies, Port Richey
- Outboard Motors, Port Richey
- Outdoor & Lawn & Garden Equipment Repair & Service, Port Richey
- Outdoor Equipment & Accessories, Port Richey
- Outdoor Furniture, Port Richey
- Outdoor Furniture & Patio Furniture, Port Richey - Garden Furniture Stores
- Outerwear Stores, Port Richey - Jackets, Sunglasses, Hats, Caps, Coats, Gloves & More
- Oxygen & Respiratory Equipment & Supplies, Port Richey - Oxygen Concentrator, Tank, Machine, etc
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