- Dance Companies, Crystal River
- Day Spas, Crystal River
- Deaf Services, Crystal River
- Delicatessen Restaurants, Crystal River
- Dental Bonding & Cosmetic Dentistry, Crystal River - Cosmetic Dentist & Tooth Bonding
- Dentists, Crystal River
- Department Stores, Crystal River
- Diabetes Services & Supplies, Crystal River - Educational, Referral & Support Service Centers
- Dialysis Clinics, Crystal River - Kidney Dialysis Centers
- Direct Mail Advertising Services, Crystal River
- Discount Stores, Crystal River - Clothing, Grocery, Furniture, Etc
- Diving Equipment & Supplies, Crystal River - Scuba & Snorkel Gear & Masks Shops
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- Diving Instruction, Crystal River
- Diving Services & Instruction, Crystal River
- Doctors, Physicians & Surgeons, Crystal River
- Donuts, Crystal River
- Doors & Door Frames, Crystal River - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drinking Establishments, Crystal River
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Crystal River
- Dry Cleaning & Laundry, Crystal River - Dry Cleaners
- Dryer Vent Cleaning, Repair & Installation, Crystal River
- Drywall, Insulation & Plaster Contractors, Crystal River - Installation & Repair Services
- Durable & Non Durable Goods & Products, Crystal River
- Dwelling Operators Except Apartment, Crystal River
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